PDRN Collagen Ampoule
One ultra-fine mist delivers firmness, volume, and a healthy glow — no dispersants, alcohol, or nitrogen gas.
What customers are saying
"I've tried a lot of mists but nothing absorbs this fast. After two weeks my skin actually looks plumper. My husband noticed before I said anything. The spray is so fine it almost feels like nothing, and then your skin is just... glowing."
"My esthetician recommended this after my microneedling session and I'm obsessed. Zero irritation. And I have very reactive skin. It calmed everything down overnight. Now I use it morning and evening and my skin has never felt this firm."
"I'm 52 and have been looking for something with PDRN for years without breaking the bank on clinic visits. This is it. The mist is incredibly light, no stickiness, and after a month my fine lines are visibly softer. I just ordered my second bottle."
Visible change. Week by week
What skin goes through when PDRN and ultra-low-molecular collagen start working together.
reported improved hydration after 2 weeks of use
noticed visibly firmer skin after 4 weeks
irritation score. Safe for even the most sensitive skin
"Fine lines look softer, my skin tone is more even, and I genuinely feel like my skin is recovering from years of stress. The mist becomes a ritual. It smells clean, feels weightless, and the results speak for themselves."
Sarah L.. Verified Customer, 6 weeks of useNon-irritating. Clinically tested and formulated without alcohol, nitrogen gas, or dispersants — a clean delivery system that helps preserve every active.
Three reasons it feels different
Ultra-Fine Mist Ampoule
Free from propellant gases, nitrogen, and dispersants. An advanced French spray system delivers active ingredients in a fine, even, refreshing veil that never feels wet or heavy.
PDRN + Collagen Synergy
300,000 ppb of salmon-derived PDRN works alongside hydrolyzed collagen to address skin concerns at their foundation while delivering visible anti-aging care.
Spray-On Fresh Collagen
Hydrolyzed collagen helps improve firmness and forms a moisture barrier that keeps skin protected, hydrated, and healthy-looking throughout the day.
An ampoule that coats your skin in collagen radiance — without the dryness
Powered by a French-engineered spray system, the PDRN Collagen Ampoule turns a high concentration of active ingredients into an ultra-fine, refreshing mist that adheres seamlessly to your facial contours. It pairs salmon-derived PDRN with ultra-low-molecular collagen to build firmness and volume from within, while a base of antioxidant-rich Red Love Apple Water restores a soft, luminous glow.
Salmon-derived bioactive DNA
300,000 ppb
PDRN (Polydeoxyribonucleotide) is a bioactive DNA complex derived from salmon. It's known to support the skin's natural recovery processes — helping activate adenosine receptors and encouraging the production of growth factors that keep skin firm, resilient, and healthy-looking.
Collagen fades faster than you think
Collagen is a fibrous protein that connects cells and tissues while holding onto moisture and firmness. Your body's natural production starts declining around age 25 — and drops sharply after 40, showing up as lost firmness and a lack of moisture.
This ampoule uses fresh, ultra-low-molecular collagen — not freeze-dried — so it's broken into smaller particles that absorb better and deliver a soft, lasting moisture glow.
Four actives, one clean formula

Salmon PDRN
Firmness, barrier support, and recovery care.

Low-Molecular Collagen
Improves skin density, refines texture, firms.

Red Love Apple Water
44% base. Antioxidant care, vitality, radiance.

Leuconostoc Ferment
Soothes, supports skin balance, holds moisture.
A collagen mist that builds a lasting barrier
Fresh collagen delivers a soft, hydrated glow and keeps skin looking radiant. Because the collagen is hydrolyzed into ultra-low-molecular particles, it absorbs deeply — for hydration and firming care that lasts, not a surface mist that evaporates.
Made for skin that needs to recover
Not all mists are created equal
| ORGAHUE PDRN Collagen Ampoule |
Standard Collagen Spray |
|
|---|---|---|
| Salmon PDRN | ✓ 300,000 ppb | ✗ None |
| Collagen molecular size | ✓ Ultra-low molecular. Absorbs deep | High-molecular. Sits on surface |
| Spray system | ✓ French micro-mist. No gas | Nitrogen / propellant gas |
| Base ingredient | ✓ 44% Red Love Apple Water | Purified water |
| Skin irritation score | ✓ 0.00. Clinically tested | Not tested |
| Alcohol-free | ✓ No alcohol | Often present |
| Dispersants | ✓ Dispersant-free | Commonly used |
| Safe post-treatment | ✓ Clinically gentle | Not recommended |
High-tech micro-mist, in three steps
Spray
Hold 20 cm from your face and mist evenly across your skin. The French micro-mist system creates an ultra-fine veil. No drips, no heaviness.
Pat
Using your fingertips, gently press the mist into skin until fully absorbed. Never rub. Patting keeps the collagen film intact and maximises absorption.
Repeat
Use every morning and evening. Before or after makeup. After cleansing, apply an appropriate amount and gently pat. Consistency is what builds results.
Tip: mist onto a clean face right after cleansing for maximum PDRN and collagen absorption.
The full Orgahue ritual
Three steps designed to work in sequence. Cleanse, treat, and amplify for maximum results.
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Vitamin B Cleanser
Niacinamide brightens and preps the skin barrier, allowing actives like PDRN to penetrate at maximum depth.
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PDRN Collagen Ampoule
300,000 ppb Salmon PDRN + ultra-low-molecular collagen mist. Apply to freshly cleansed skin for deepest absorption.
✓ Current product
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RG Vita Cell EGF Ampoule
EGF layered on PDRN creates a dual regeneration signal. The two actives work synergistically to support skin renewal.
Shop $159.90 →Frequently asked
Can I use it over makeup?
Yes. The ultra-fine micro-mist is designed to be used before and after makeup application. It sets makeup, adds a dewy finish, and delivers active ingredients without disturbing coverage. Hold the bottle 20 cm away and mist lightly.
When will I start seeing results?
Most customers notice improved hydration and a visible glow within the first 1. 2 weeks. Firming and texture improvement from the PDRN and collagen synergy typically becomes noticeable at 3. 4 weeks of consistent AM + PM use.
Is it suitable for sensitive or post-treatment skin?
Absolutely. The PDRN Collagen Ampoule has been clinically tested with a skin irritation score of 0.00. Meaning it is classified as non-irritating. It contains no alcohol, no nitrogen gas, and no dispersants. It is frequently recommended for use after microneedling, laser, and other aesthetic procedures.
What exactly is PDRN?
PDRN (Polydeoxyribonucleotide) is a bioactive DNA complex derived from purified salmon. It is known for activating adenosine receptors and supporting the skin's natural recovery and regeneration processes. Our formula contains 300,000 ppb of salmon-derived PDRN. One of the highest concentrations available in an at-home product.
How long does one bottle last?
With regular AM + PM use (2. 3 sprays per session), one 60 ml bottle typically lasts 6. 8 weeks. Because the mist is so fine, very little product is used per application. Making it highly efficient for daily use.
Can I use it with retinol or acids?
Yes. Because the formula is alcohol-free and has a 0.00 irritation score, it pairs well with active ingredients like retinol and AHAs. We recommend using it as a first step after cleansing, allowing it to absorb before applying any actives. It can also be used as a soothing layer after actives to support recovery.
Start your PDRN ritual today
300,000 ppb Salmon PDRN · Ultra-Low Molecular Collagen · 0.00 Irritation
Specifications
| Product | Orgahue PDRN Collagen Ampoule — Recovery Ampoule Mist |
| Volume | 60 ml / 2.03 fl.oz |
| Texture | High-tech micro-mist ampoule |
| Key actives | Salmon PDRN (300,000 ppb), ultra-low-molecular hydrolyzed collagen, 44% Red Love Apple Water, Leuconostoc Ferment |
| Free from | Nitrogen gas, dispersants, alcohol, purified water |
| Testing | Skin irritation test completed — 0.00 (non-irritating) |
| Use | Morning & evening; suitable before and after makeup |